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ACTN1 抗体 (N-Term)

ACTN1 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787669
发货至: 中国
  • 抗原 See all ACTN1 抗体
    ACTN1 (Actinin, alpha 1 (ACTN1))
    抗原表位
    • 14
    • 12
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 58
    • 20
    • 17
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬, 马, 斑马鱼
    宿主
    • 47
    • 11
    • 1
    克隆类型
    • 49
    • 10
    多克隆
    标记
    • 34
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACTN1 antibody is un-conjugated
    应用范围
    • 41
    • 26
    • 20
    • 18
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    DHYDSQQTND YMQPEEDWDR DLLLDPAWEK QQRKTFTAWC NSHLRKAGTQ
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against ACTN1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ACTN1
    Top Product
    Discover our top product ACTN1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 892 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ACTN1 (Actinin, alpha 1 (ACTN1))
    别名
    ACTN1 (ACTN1 产品)
    别名
    ACTN1 antibody, actinin antibody, BDPLT15 antibody, 3110023F10Rik antibody, Actn1a antibody, actinin alpha 1 antibody, actinin, alpha 1 antibody, actinin alpha 1 L homeolog antibody, ACTN1 antibody, actn1 antibody, Actn1 antibody, actn1.L antibody
    背景
    Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ40884
    Protein Interaction Partner: SPERT, KCTD6, MICALL2, MYOZ2, EPM2AIP1, OAS1, ACTN3, ACTN1, SUMO2, SUMO3, HSF5, UBC, MDM2, EZH2, BMI1, ACTN4, CDAN1, DCAF8, SF3A3, STAM2, SRP19, UBD, IGSF8, ICAM1, CD81, ERBB2IP, SVIL, PDHX, RPS27, PSMA1, KPNA2, HCVgp1, PIAS4, GIT2, NUMBL, HSP90AB1, HSP90
    Protein Size: 892
    分子量
    103 kDa
    基因ID
    87
    NCBI登录号
    NM_001102, NP_001093
    UniProt
    P12814
    途径
    Cell-Cell Junction Organization
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