CBX2 抗体 (Middle Region)
-
- 抗原 See all CBX2 抗体
- CBX2 (Chromobox Homolog 2 (CBX2))
-
抗原表位
- Middle Region
-
适用
- 人, 大鼠, Cow, 马, Pig
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CBX2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- SDSDPDSASP PSTGQNPSVS VQTSQDWKPT RSLIEHVFVT DVTANLITVT
- 预测反应
- Cow: 86%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against CBX2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CBX2
- Top Product
- Discover our top product CBX2 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 532 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- CBX2 (Chromobox Homolog 2 (CBX2))
- 别名
- CBX2 (CBX2 产品)
- 别名
- cbx2 antibody, M33 antibody, pc1 antibody, wu:fd20e09 antibody, zgc:103563 antibody, MOD2 antibody, pc antibody, CDCA6 antibody, SRXY5 antibody, cdca6 antibody, m33 antibody, chromobox 2 antibody, chromobox homolog 2 (Drosophila Pc class) antibody, chromobox 2 L homeolog antibody, cbx2 antibody, CBX2 antibody, Cbx2 antibody, cbx2.L antibody
- 背景
-
CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: CDCA6, M33, MGC10561, SRXY5
Protein Interaction Partner: KRTAP10-3, KRTAP10-1, KRTAP10-9, KRTAP10-7, RBMY1F, DHX57, KRTAP2-4, RBMY1A1, RNF2, BMI1, MDFI, SOX2, GTF2I, PHC2, CSNK2B, CSNK2A2, CSNK2A1, CENPE, PARP1, CCDC158, DIS3L2, HIST4H4, CBX2, PARP12, RNF213, ZKSCAN7, DCAF6, KDM3A, MYCBP2, ANKRD26, PSME3, TRANK
Protein Size: 532 - 分子量
- 56 kDa
- 基因ID
- 84733
- NCBI登录号
- NM_005189, NP_005180
- UniProt
- Q14781
-