TNKS1BP1 抗体 (Middle Region)
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- 抗原 See all TNKS1BP1 抗体
- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNKS1BP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DGEASQTEDV DGTWGSSAAR WSDQGPAQTS RRPSQGPPAR SPSQDFSFIE
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TNKS1BP1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TNKS1BP1
- Top Product
- Discover our top product TNKS1BP1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1729 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
- 别名
- TNKS1BP1 (TNKS1BP1 产品)
- 背景
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TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
Alias Symbols: FLJ45975, KIAA1741, TAB182
Protein Interaction Partner: UBC, RNF219, SPC25, RABGEF1, DCTN3, SPTBN1, NLK, CSNK2A1, CNOT6L, CNOT6, VCP, HNRNPK, DYNC1H1, CBX3, SIRT7, TSG101, Cnot3, Capza1, TNKS2, TNKS,
Protein Size: 1729 - 分子量
- 190 kDa
- 基因ID
- 85456
- NCBI登录号
- NM_033396, NP_203754
- UniProt
- Q9C0C2
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