POT1 抗体 (Middle Region)
-
- 抗原 See all POT1 抗体
- POT1 (Protection of Telomeres 1 (POT1))
-
抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 豚鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This POT1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- MNSENQTMLS LEFHLHGGTS YGRGIRVLPE SNSDVDQLKK DLESANLTAN
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against POT1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human POT1
- Top Product
- Discover our top product POT1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 634 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- POT1 (Protection of Telomeres 1 (POT1))
- 别名
- POT1 (POT1 产品)
- 别名
- HPOT1 antibody, POT1 antibody, DKFZp469P1825 antibody, pot1 antibody, 1500031H18Rik antibody, AI851169 antibody, Pot1 antibody, Pot1a antibody, protection of telomeres 1 antibody, protection of telomeres 1 L homeolog antibody, protection of telomeres 1A antibody, POT1 antibody, pot1.L antibody, Pot1a antibody, Pot1 antibody
- 背景
-
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Alias Symbols: DKFZP586D211, hPot1, HPOT1
Protein Interaction Partner: TPP1, CFL2, ACD, CORO1A, KHDRBS1, LAMC3, BCAS2, MVP, ZNF32, ECI1, CSNK2B, COX6A2, ALDH1A1, ACTN4, SERTAD1, C2orf74, ZBTB49, ZBED2, CYP4F11, MYO5C, RIF1, NAP1L1, MDM2, KRT18, GRN, PACSIN1, SULT4A1, PGLS, AIPL1, SH3BP1, HAAO, NCDN, TWF2, ACOT7, DDX19B, PACS
Protein Size: 634 - 分子量
- 70 kDa
- 基因ID
- 25913
- NCBI登录号
- NM_015450, NP_056265
- UniProt
- Q9NUX5
- 途径
- Cell Division Cycle, Telomere Maintenance
-