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H2AFY 抗体 (Middle Region)

H2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787622
发货至: 中国
  • 抗原 See all H2AFY 抗体
    H2AFY (H2A Histone Family, Member Y (H2AFY))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 23
    • 18
    • 17
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, Pig
    宿主
    • 23
    克隆类型
    • 14
    • 9
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This H2AFY antibody is un-conjugated
    应用范围
    • 16
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PVSKKAGGKK GARKSKKQGE VSKAASADST TEGTPADGFT VLSTKSLFLG
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against H2AFY. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human H2AFY
    Top Product
    Discover our top product H2AFY Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 371 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    H2AFY (H2A Histone Family, Member Y (H2AFY))
    别名
    H2AFY (H2AFY 产品)
    别名
    H2A.y antibody, H2A/y antibody, H2AF12M antibody, H2AFJ antibody, MACROH2A1.1 antibody, mH2A1 antibody, macroH2A1.2 antibody, mH2a1 antibody, macroH2A1 antibody, wu:fa93c12 antibody, zgc:136891 antibody, h2a.y antibody, h2a/y antibody, h2af12m antibody, h2afj antibody, macroh2a antibody, mh2a1 antibody, core histone macro-H2A.1 antibody, H2A histone family, member Y antibody, H2A histone family member Y antibody, H2A histone family member Y L homeolog antibody, LOC100230612 antibody, H2AFY antibody, LOC481514 antibody, H2afy antibody, h2afy antibody, h2afy.L antibody
    背景
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: H2A.y, H2A/y, H2AF12M, H2AFJ, MACROH2A1.1, mH2A1, macroH2A1.2
    Protein Interaction Partner: ERICH2, UBC, SUMO2, SUMO3, HIST1H3A, H3F3A, SUZ12, EED, RNF2, EZH2, BMI1, SRPK1, LMNA, ATF2, FN1, HIST1H3B, CENPA, APP, CBX5, CBX3, DIDO1, UBD, ATXN1L, NEDD8, ERBB2, SUMO1, HDGF, HDAC2, HDAC1, PARP1, tat, CUL3, SPOP, WDR77, PHF14, DEK, XRCC5, TOP1, RAN, H
    Protein Size: 371
    分子量
    39 kDa
    基因ID
    9555
    NCBI登录号
    NM_001040158, NP_001035248
    UniProt
    O75367
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