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CENPH 抗体 (Middle Region)

CENPH 适用: 人, 小鼠, 大鼠, Pig, 犬, 马, 豚鼠, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787617
发货至: 中国
  • 抗原 See all CENPH 抗体
    CENPH (Centromere Protein H (CENPH))
    抗原表位
    • 15
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Pig, 犬, 马, 豚鼠, 兔, Cow
    宿主
    • 43
    • 8
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CENPH antibody is un-conjugated
    应用范围
    • 44
    • 18
    • 13
    • 13
    • 12
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    序列
    ESWDLEEKLL DIRKKRLQLK QASESKLLEI QTEKNKQKID LDSMENSERI
    预测反应
    Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against CENPH. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CENPH
    Top Product
    Discover our top product CENPH Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 247 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Liao, Zhang, Zhou, Zimonjic, Mani, Kaba, Gifford, Reinhardt, Popescu, Guo, Eaton, Lodish, Weinberg: "Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity." in: Cancer research, Vol. 67, Issue 17, pp. 8131-8, (2007) (PubMed).

  • 抗原
    CENPH (Centromere Protein H (CENPH))
    别名
    CENPH (CENPH 产品)
    别名
    1700021I11Rik antibody, 2410018A12Rik antibody, 2610042E16Rik antibody, 2810046K12Rik antibody, AU044255 antibody, CENP-H antibody, ENP antibody, si:dkey-186m8.3 antibody, cenp-h antibody, centromere protein H antibody, centromere protein H pseudogene antibody, CENPH antibody, Cenph antibody, cenph antibody, LOC100356112 antibody, LOC101788801 antibody
    背景
    Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: NNF1, PMF1
    Protein Interaction Partner: CENPH, CENPK, MTAP, NDC80, NUF2, SUGT1, UBC, VCP, CENPU, CENPN, CENPA, TRIM36, CENPP, CENPO, CENPI, ELAVL1, KIF2C, PMVK,
    Protein Size: 247
    分子量
    27 kDa
    基因ID
    64946
    NCBI登录号
    NM_022909, NP_075060
    UniProt
    Q9H3R5
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