CENPH 抗体 (N-Term)
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- 抗原 See all CENPH 抗体
- CENPH (Centromere Protein H (CENPH))
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抗原表位
- N-Term
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适用
- 人, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CENPH antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT
- 预测反应
- Human: 100%, Pig: 86%
- 产品特性
- This is a rabbit polyclonal antibody against CENPH. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CENPH
- Top Product
- Discover our top product CENPH Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 247 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CENPH (Centromere Protein H (CENPH))
- 别名
- CENPH (CENPH 产品)
- 别名
- 1700021I11Rik antibody, 2410018A12Rik antibody, 2610042E16Rik antibody, 2810046K12Rik antibody, AU044255 antibody, CENP-H antibody, ENP antibody, si:dkey-186m8.3 antibody, cenp-h antibody, centromere protein H antibody, centromere protein H pseudogene antibody, CENPH antibody, Cenph antibody, cenph antibody, LOC100356112 antibody, LOC101788801 antibody
- 背景
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Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
Alias Symbols: NNF1, PMF1
Protein Interaction Partner: CENPH, CENPK, MTAP, NDC80, NUF2, SUGT1, UBC, VCP, CENPU, CENPN, CENPA, TRIM36, CENPP, CENPO, CENPI, ELAVL1, KIF2C, PMVK,
Protein Size: 247 - 分子量
- 27 kDa
- 基因ID
- 64946
- NCBI登录号
- NM_022909, NP_075060
- UniProt
- Q9H3R5
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