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- 抗原 See all MED14 抗体
- MED14 (Mediator Complex Subunit 14 (MED14))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MED14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 序列
- AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE
- 预测反应
- Human: 100%, Mouse: 79%, Rabbit: 86%
- 产品特性
- This is a rabbit polyclonal antibody against MED14. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MED14
- Top Product
- Discover our top product MED14 Primary Antibody
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anti-Mediator Complex Subunit 14 (MED14) (Internal Region) antibody
MED14 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 14 (MED14) (AA 586-615) antibodyMED14 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB20179 unconjugated
anti-Mediator Complex Subunit 14 (MED14) antibodyMED14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 14 (MED14) (AA 575-624) antibodyMED14 适用: 人, 小鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 14 (MED14) (AA 701-750) antibodyMED14 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1454 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MED14 (Mediator Complex Subunit 14 (MED14))
- 别名
- MED14 (MED14 产品)
- 别名
- CG12031 antibody, Dmel\\CG12031 antibody, Med14 antibody, Trap170 antibody, dTRAP170 antibody, p160 antibody, EXLM1 antibody, crsp150 antibody, crsp2 antibody, trap170 antibody, wu:fd21c05 antibody, wu:fk28h11 antibody, CRSP2 antibody, NV18605 antibody, CRSP150 antibody, CSRP antibody, CXorf4 antibody, DRIP150 antibody, RGR1 antibody, TRAP170 antibody, 9930001L01Rik antibody, AU041628 antibody, Crsp2 antibody, ENSMUSG00000073278 antibody, Gm641 antibody, ORF1 antibody, RGD1560170 antibody, Mediator complex subunit 14 antibody, mediator complex subunit 14 antibody, mediator of RNA polymerase II transcription subunit 14 antibody, transcriptional regulation antibody, MED14 antibody, med14 antibody, LOC100113592 antibody, Med14 antibody, RGR1 antibody
- 背景
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Alias Symbols: CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, MGC104513, RGR1, TRAP170
Protein Interaction Partner: UBC, HECW2, CDK8, CDK19, MED12, ESR1, MED19, MED26, PPARG, FBXW7, EPAS1, MED11, MED8, MED29, MED18, MED4, PPP6R1, MED16, MED13, MED24, MED27, MED17, MED21, MED1, CTDP1, SREBF1, DCTN1, ACTN2, ACTN1, MED10, UACA, NECAB2, MED25, MED15, CRSP5, MED7, MED23, VD
Protein Size: 1454 - 分子量
- 160 kDa
- 基因ID
- 9282
- NCBI登录号
- NM_004229, NP_004220
- UniProt
- O60244
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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