Glutaredoxin 2 抗体 (Middle Region)
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- 抗原 See all Glutaredoxin 2 (GRX2) 抗体
- Glutaredoxin 2 (GRX2)
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抗原表位
- Middle Region
- 适用
- 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutaredoxin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- NVNYKVVELD LLEYGNQFQD ALYKMTGERT VPRIFVNGTF IGGATDTHRL H
- 预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%, Sheep: 86%
- 产品特性
- This is a rabbit polyclonal antibody against GLRX2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GLRX2
- Top Product
- Discover our top product GRX2 Primary Antibody
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anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibody
GRX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 120-146), (C-Term) antibodyGRX2 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18221 unconjugated
anti-Glutaredoxin 2 (GRX2) (Middle Region) antibodyGRX2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 126-155), (C-Term) antibodyGRX2 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 101-164) antibodyGRX2 适用: 人, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-164) antibodyGRX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 91-141) antibodyGRX2 适用: 人, Cow, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 164 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Glutaredoxin 2 (GRX2)
- 别名
- GLRX2 (GRX2 产品)
- 别名
- ECK1049 antibody, JW1051 antibody, CGI-133 antibody, GRX2 antibody, 1700010P22Rik antibody, AI645710 antibody, Grx2 antibody, glutaredoxin 2 (Grx2) antibody, glutaredoxin Grx2 antibody, thioredoxin antibody, glutaredoxin 2 antibody, glutaredoxin 2 (thioltransferase) antibody, grxB antibody, grx2 antibody, AF_RS10790 antibody, GLRX2 antibody, Glrx2 antibody
- 背景
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GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression of GLRX2 decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Alias Symbols: GRX2, bA101E13.1, CGI-133
Protein Interaction Partner: BAG3, TXNRD1,
Protein Size: 164 - 分子量
- 18 kDa
- 基因ID
- 51022
- NCBI登录号
- NM_197962, NP_932066
- UniProt
- Q9NS18
- 途径
- Cell RedoxHomeostasis
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