PLAT 抗体 (Middle Region)
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- 抗原 See all PLAT 抗体
- PLAT (Plasminogen Activator, Tissue (PLAT))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, Pig, 兔, 豚鼠, Cow, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLAT antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TVILGRTYRV VPGEEEQKFE VEKYIVHKEF DDDTYDNDIA LLQLKSDSSR
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 82%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PLAT. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PLAT
- Top Product
- Discover our top product PLAT Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 516 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PLAT (Plasminogen Activator, Tissue (PLAT))
- 别名
- PLAT (PLAT 产品)
- 别名
- T-PA antibody, TPA antibody, AU020998 antibody, AW212668 antibody, D8Ertd2e antibody, tPA antibody, PATISS antibody, tpa antibody, Plat antibody, plat antibody, t-pa antibody, plasminogen activator, tissue type antibody, plasminogen activator, tissue antibody, chromosome 20 open reading frame 181 antibody, plasminogen activator, tissue L homeolog antibody, PLAT antibody, Plat antibody, plat antibody, C20orf181 antibody, plat.L antibody
- 背景
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This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: DKFZp686I03148, T-PA, TPA
Protein Interaction Partner: PDGFC, POT1, TERF2, CKAP4, LRP1B, GRIN1, SERPING1, SERPINI1, SERPINA5, MAPK3, LAMA3, F10, PLAU, CLEC3B, SPARC, MAPK1, PLAT, SERPINE1, PLG, HMGB1, ANXA2, LAMA1, KRT8, FGA, CALR, LRP1, FN1, LAMA5, F2,
Protein Size: 516 - 分子量
- 53 kDa
- 基因ID
- 5327
- NCBI登录号
- NM_033011, NP_127509
- 途径
- Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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