CALCOCO1 抗体 (N-Term)
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- 抗原 See all CALCOCO1 抗体
- CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CALCOCO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ESTTDGSPIH TSVQFQASYL PKPGAQLYQF RYVNRQGQVC GQSPPFQFRE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CALCOCO1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CALCOCO1
- Top Product
- Discover our top product CALCOCO1 Primary Antibody
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anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (AA 462-691) antibody
CALCOCO1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) antibodyCALCOCO1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (AA 1-691) antibodyCALCOCO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) antibodyCALCOCO1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) antibodyCALCOCO1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (AA 71-120) antibodyCALCOCO1 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 691 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))
- 别名
- CALCOCO1 (CALCOCO1 产品)
- 别名
- Cocoa antibody, calphoglin antibody, fa11a10 antibody, wu:fa11a10 antibody, CALCOCO1 antibody, Xdsg antibody, cocoa antibody, dsgc antibody, pp13275 antibody, 1810009B06Rik antibody, Gcap11 antibody, mKIAA1536 antibody, calcium binding and coiled-coil domain 1 antibody, calcium binding and coiled-coil domain 1a antibody, calcium binding and coiled-coil domain 1 S homeolog antibody, calcium binding and coiled-coil domain 1 L homeolog antibody, calcium binding and coiled coil domain 1 antibody, CALCOCO1 antibody, calcoco1a antibody, calcoco1.S antibody, calcoco1.L antibody, Calcoco1 antibody
- 背景
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CALCOCO1 functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR).CALCOCO1 is recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation CALCOCO1 acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. CALCOCO1 is involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. CALCOCO1 functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions.
Alias Symbols: Cocoa, KIAA1536, PP13275, calphoglin
Protein Interaction Partner: CWF19L2, CEP19, FAM161A, TBC1D15, DUSP13, ISOC1, GABARAPL2, NDC80, UBC, GRIK2, APP, APTX, EP300, CTNNB1, NEDD4, HIST1H4A, HIST1H3A, PCBD1, TBC1D17, CTNNBL1, CYTH3, SH3GL3, CRYBA2, CREBBP, MAPK1, KRT15, IPP, FOSL1,
Protein Size: 691 - 分子量
- 77 kDa
- 基因ID
- 57658
- NCBI登录号
- NM_020898, NP_065949
- UniProt
- Q9P1Z2
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding
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