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PKC eta 抗体 (N-Term)

PRKCH 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786852
发货至: 中国
  • 抗原 See all PKC eta (PRKCH) 抗体
    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
    抗原表位
    • 10
    • 9
    • 7
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    • 6
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 51
    • 30
    • 16
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, 犬, Pig
    宿主
    • 60
    • 4
    克隆类型
    • 61
    • 2
    多克隆
    标记
    • 38
    • 8
    • 7
    • 5
    • 3
    • 3
    This PKC eta antibody is un-conjugated
    应用范围
    • 54
    • 39
    • 26
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KKGHQLLDPY LTVSVDQVRV GQTSTKQKTN KPTYNEEFCA NVTDGGHLEL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against PRKCH. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCH
    Top Product
    Discover our top product PRKCH Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 683 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
    别名
    PRKCH (PRKCH 产品)
    别名
    PKC-L antibody, PKCL antibody, PRKCL antibody, nPKC-eta antibody, Pkch antibody, pkc-eta antibody, PRKCH antibody, prkch antibody, si:ch211-212g7.5 antibody, zgc:172124 antibody, protein kinase C eta antibody, protein kinase C, eta antibody, protein kinase C eta L homeolog antibody, protein kinase C, eta, b antibody, protein kinase C, eta, a antibody, protein kinase C epsilon antibody, PRKCH antibody, Prkch antibody, prkch.L antibody, prkchb antibody, prkcha antibody, prkch antibody, PRKCE antibody
    背景
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
    Alias Symbols: MGC26269, MGC5363, PKC-L, PKCL, PRKCL, nPKC-eta
    Protein Interaction Partner: BANP, HSP90AA1, GSK3A, PPP1R14A, UBC, VHL, PRKCH, NFE2L2, MGMT, ZBTB8OS, PARD6A, PRKD1, NUMB, ITGB2, SRC, PTPN11, FYN, CDK2, PDPK1, AKAP13,
    Protein Size: 683
    分子量
    78 kDa
    基因ID
    5583
    NCBI登录号
    NM_006255, NP_006246
    UniProt
    P24723
    途径
    Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
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