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RASGRF1 抗体 (Middle Region)

RASGRF1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786746
发货至: 中国
  • 抗原 See all RASGRF1 抗体
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    抗原表位
    • 15
    • 12
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 26
    • 25
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 50
    克隆类型
    • 50
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASGRF1 antibody is un-conjugated
    应用范围
    • 33
    • 22
    • 15
    • 13
    • 13
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PMSEKGKITR GRLGSLSLKK EGERQCFLFS KHLIICTRGS GGKLHLTKNG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against RASGRF1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RASGRF1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1273 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    别名
    RASGRF1 (RASGRF1 产品)
    别名
    CDC25 antibody, CDC25L antibody, GNRP antibody, GRF1 antibody, GRF55 antibody, H-GRF55 antibody, PP13187 antibody, ras-GRF1 antibody, AI844718 antibody, CDC25Mm antibody, Grf1 antibody, Grfbeta antibody, P190-A antibody, Ras-GRF1 antibody, p190 antibody, p190RhoGEF antibody, cdc25 antibody, rasgrf1 antibody, Ras protein specific guanine nucleotide releasing factor 1 antibody, RAS protein-specific guanine nucleotide-releasing factor 1 antibody, Ras protein specific guanine nucleotide releasing factor 1 S homeolog antibody, si:ch211-234p18.3 antibody, RASGRF1 antibody, Rasgrf1 antibody, rasgrf1.S antibody, si:ch211-234p18.3 antibody, rasgrf1 antibody
    背景
    The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
    Protein Interaction Partner: EHD4, SNRNP70, CEBPA, ADRBK1, MYC, UBC, TNK2, YWHAE, USP8, RAC1, PRKACA, NTRK2, RRAS2, NTRK3, NTRK1, RHOA, YWHAB, PPP1R9B, MARK3, HRAS,
    Protein Size: 1273
    分子量
    145 kDa
    基因ID
    5923
    NCBI登录号
    NM_002891, NP_002882
    UniProt
    Q13972
    途径
    RTK signaling, Cell Division Cycle, M Phase
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