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PKC iota 抗体 (Middle Region)

PRKCI 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786697
发货至: 中国
  • 抗原 See all PKC iota (PRKCI) 抗体
    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
    抗原表位
    • 15
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 40
    • 33
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 36
    • 4
    克隆类型
    • 36
    • 4
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKC iota antibody is un-conjugated
    应用范围
    • 32
    • 15
    • 13
    • 13
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    TVIPYNPSSH ESLDQVGEEK EAMNTRESGK ASSSLGLQDF DLLRVIGRGS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PRKCI. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PRKCI
    Top Product
    Discover our top product PRKCI Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 596 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
    别名
    PRKCI (PRKCI 产品)
    别名
    DXS1179E antibody, PKCI antibody, nPKC-iota antibody, aPKC[l] antibody, hal antibody, has antibody, PRKCI antibody, PKC antibody, 2310021H13Rik antibody, AI427505 antibody, PKClambda antibody, Pkci antibody, Pkcl antibody, Prkcl antibody, aPKClambda antibody, mKIAA4165 antibody, protein kinase C iota antibody, protein kinase C, iota antibody, PRKCI antibody, prkci antibody, Prkci antibody
    背景
    This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
    Alias Symbols: DXS1179E, MGC26534, PKCI, nPKC-iota
    Protein Interaction Partner: PARD6B, PARD6A, UBC, AMOT, SQSTM1, CRX, NPM1, IKBKG, YWHAE, IL1RAP, HSP90AA1, GAB1, CASP8, PARD3, APP, UBD, MAP2K5, MARK2, ARHGAP17, TJP1, ELAVL1, CDK7, MBP, TSC22D1, TTR, FABP4, PARD6G, MARK4, CDC37, RAPGEF2, PNMA1, NIPSNAP1, YWHAZ, YWHAH, MYO10, LLGL1,
    Protein Size: 596
    分子量
    68 kDa
    基因ID
    5584
    NCBI登录号
    NM_002740, NP_002731
    UniProt
    P41743
    途径
    Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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