PRKACB 抗体 (N-Term)
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- 抗原 See all PRKACB 抗体
- PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, Cow, 马, 兔, 豚鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKACB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PRKACB. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRKACB
- Top Product
- Discover our top product PRKACB Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 257 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))
- 别名
- PRKACB (PRKACB 产品)
- 别名
- PKACB antibody, XPKAbeta antibody, kin-1 antibody, pkacb antibody, prkacba antibody, PRKACB antibody, prkacb antibody, wu:fz54b03 antibody, zgc:110804 antibody, Pkacb antibody, protein kinase cAMP-activated catalytic subunit beta antibody, protein kinase cAMP-activated catalytic subunit beta S homeolog antibody, protein kinase, cAMP-dependent, catalytic, beta antibody, protein kinase, cAMP-dependent, catalytic, beta b antibody, protein kinase, cAMP dependent, catalytic, beta antibody, PRKACB antibody, prkacb.S antibody, prkacb antibody, Prkacb antibody, prkacbb antibody
- 背景
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CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.
Alias Symbols: DKFZp781I2452, MGC41879, MGC9320, PKACB
Protein Interaction Partner: APPBP2, UBC, TP53RK, TPRKB, KIAA1279, ARPC2, ACTR2, ACTR3, ARPC1B, ARPC4, SUMO1, PFDN1, CDK5RAP2, MAPRE1, AKAP11, DCAF7, AKAP9, TRAP1, PDE4DIP, AKAP5, AKAP7, VAPA, VAPB, DYNLL1, AKAP1, RPS6, RPL27A, PRKAR2B, PRKAR2A, PRKAR1B, PRKAR1A, PRKACA, HSP90AB1, HS
Protein Size: 257 - 分子量
- 28 kDa
- 基因ID
- 5567
- NCBI登录号
- NM_207578, NP_997461
- UniProt
- P22694
- 途径
- AMPK Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism
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