MVK 抗体 (Middle Region)
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- 抗原 See all MVK 抗体
- MVK (Mevalonate Kinase (MVK))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔, 斑马鱼, Pig, Saccharomyces cerevisiae, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MVK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KEDLELINKW AFQGERMIHG NPSGVDNAVS TWGGALRYHQ GKISSLKRSP
- 预测反应
- Cow: 100%, Dog: 86%, Goat: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against MVK. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MVK
- Top Product
- Discover our top product MVK Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 396 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MVK (Mevalonate Kinase (MVK))
- 别名
- MVK (MVK 产品)
- 背景
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MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
Alias Symbols: LRBP, MVLK, MK
Protein Interaction Partner: MVK, PPP1CB, GSS, MAT1A, POT1, TERF1, UBC, EWSR1,
Protein Size: 396 - 分子量
- 42 kDa
- 基因ID
- 4598
- NCBI登录号
- NM_000431, NP_000422
- UniProt
- Q03426
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