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MVK 抗体 (Middle Region)

MVK 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔, 斑马鱼, Pig, Saccharomyces cerevisiae, 山羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786519
发货至: 中国
  • 抗原 See all MVK 抗体
    MVK (Mevalonate Kinase (MVK))
    抗原表位
    • 10
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔, 斑马鱼, Pig, Saccharomyces cerevisiae, 山羊
    宿主
    • 32
    • 5
    克隆类型
    • 34
    • 3
    多克隆
    标记
    • 27
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This MVK antibody is un-conjugated
    应用范围
    • 31
    • 16
    • 11
    • 11
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    KEDLELINKW AFQGERMIHG NPSGVDNAVS TWGGALRYHQ GKISSLKRSP
    预测反应
    Cow: 100%, Dog: 86%, Goat: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against MVK. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MVK
    Top Product
    Discover our top product MVK Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 396 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MVK (Mevalonate Kinase (MVK))
    别名
    MVK (MVK 产品)
    背景
    MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
    Alias Symbols: LRBP, MVLK, MK
    Protein Interaction Partner: MVK, PPP1CB, GSS, MAT1A, POT1, TERF1, UBC, EWSR1,
    Protein Size: 396
    分子量
    42 kDa
    基因ID
    4598
    NCBI登录号
    NM_000431, NP_000422
    UniProt
    Q03426
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