BLMH 抗体 (Middle Region)
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- 抗原 See all BLMH 抗体
- BLMH (Bleomycin Hydrolase (BLMH))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 犬, 豚鼠, 斑马鱼, Cow, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BLMH antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EYLSNMVGGR KTLYNNQPID FLKKMVAASI KDGEAVWFGC DVGKHFNSKL
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against BLMH. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BLMH
- Top Product
- Discover our top product BLMH Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 455 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- BLMH (Bleomycin Hydrolase (BLMH))
- 别名
- BLMH (BLMH 产品)
- 别名
- AI035728 antibody, Bh antibody, Bmh antibody, wu:fb13c01 antibody, zgc:66261 antibody, bh antibody, bmh antibody, BH antibody, BMH antibody, bleomycin hydrolase antibody, Bleomycin hydrolase antibody, bleomycin hydrolase S homeolog antibody, BLMH antibody, pepC antibody, LOC5569945 antibody, Apre_0140 antibody, Apar_0899 antibody, Smon_1289 antibody, Kfla_1242 antibody, Snas_3912 antibody, BLJ_1941 antibody, Olsu_1085 antibody, PGTDC60_0106 antibody, Blmh antibody, blmh antibody, blmh.S antibody
- 背景
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The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BH, BMH
Protein Interaction Partner: NUDT12, WDYHV1, BLMH, UBC, ZBTB1, SH3GLB2, LZTFL1, GORASP2, PES1, GTF2A1, AP1M2, CYP2C8, RNF32, ECSIT, MAST1, COPS5, CUL4B, SUMO2, PDPK1, Fam134a, USP53, KBTBD7, RPL11, UBE2I, TRIO, RPL29, APP,
Protein Size: 455 - 分子量
- 52 kDa
- 基因ID
- 642
- NCBI登录号
- NM_000386, NP_000377
- UniProt
- Q13867
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