PEX5 抗体 (N-Term)
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- 抗原 See all PEX5 抗体
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PEX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TATDRWYDEY HPEEDLQHTA SDFVAKVDDP KLANSEFLKF VRQIGEGQVS
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PEX5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PEX5
- Top Product
- Discover our top product PEX5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 631 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
- 别名
- PEX5 (PEX5 产品)
- 背景
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PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD).
Alias Symbols: PTS1R, PXR1, PTS1-BP
Protein Interaction Partner: CAPRIN2, CCDC14, TOMM7, PRR13, GDPD5, ZNF772, EP400NL, TM6SF1, ACOT8, RPL14, MKRN3, S100A6, LDHB, RANBP6, GSTK1, ZADH2, TYSND1, HSDL2, ACAD11, LONP2, PECR, HSD17B4, HOXA7, EHHADH, ECH1, CRAT, CAT, BRCA1, ACOX1, DECR2, HACL1, DHRS4, ECI2, AGPS, GNPAT, UBC,
Protein Size: 631 - 分子量
- 70 kDa
- 基因ID
- 5830
- NCBI登录号
- NM_000319, NP_000310
- 途径
- Monocarboxylic Acid Catabolic Process
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