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SPAG8 抗体 (Middle Region)

SPAG8 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786290
发货至: 中国
  • 抗原 See all SPAG8 抗体
    SPAG8 (Sperm Associated Antigen 8 (SPAG8))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 兔, Cow, 犬, Pig
    宿主
    • 51
    • 4
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPAG8 antibody is un-conjugated
    应用范围
    • 29
    • 23
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PAPTKPHDYR QEQPETFWIQ RAPQLPTWWP LPTQVPAAED YLTWKEWGFT
    预测反应
    Cow: 79%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against SPAG8. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SPAG8
    Top Product
    Discover our top product SPAG8 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 501 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Dyrbye, Broholm, Dziegiel, Laursen: "The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population." in: European journal of epidemiology, Vol. 23, Issue 1, pp. 23-7, (2008) (PubMed).

  • 抗原
    SPAG8 (Sperm Associated Antigen 8 (SPAG8))
    别名
    SPAG8 (SPAG8 产品)
    别名
    BS-84 antibody, HSD-1 antibody, SMP1 antibody, SPAG3 antibody, hSMP-1 antibody, MH-SPAG8 antibody, sperm associated antigen 8 antibody, SPAG8 antibody, Spag8 antibody
    背景
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
    Alias Symbols: BS-84, HSD-1, MGC26201, SMP1, SPAG3, hSMP-1
    Protein Interaction Partner: KLHL32, DTX2, SNRPC, CSTF2, PITX1, JMJD4, WHSC1L1, KDM3B, CARM1, PRMT5, PRMT1, PRMT2, RANBP9, UBQLN4, NEDD4L, RAN,
    Protein Size: 501
    分子量
    53 kDa
    基因ID
    26206
    NCBI登录号
    NM_172312, NP_758516
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