ALKBH3 抗体 (Middle Region)
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- 抗原 See all ALKBH3 抗体
- ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALKBH3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EMRKKPPPEE NGDYTYVERV KIPLDHGTLL IMEGATQADW QHRVPKEYHS
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ALKBH3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ALKBH3
- Top Product
- Discover our top product ALKBH3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 286 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage." in: The EMBO journal, Vol. 25, Issue 14, pp. 3389-97, (2006) (PubMed).
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Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage." in: The EMBO journal, Vol. 25, Issue 14, pp. 3389-97, (2006) (PubMed).
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- 抗原
- ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
- 别名
- ALKBH3 (ALKBH3 产品)
- 别名
- ABH3 antibody, DEPC-1 antibody, DEPC1 antibody, PCA1 antibody, 1700108H04Rik antibody, 1810020C19Rik antibody, Abh3 antibody, mABH3 antibody, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog antibody, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase antibody, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase antibody, alkbh3.L antibody, ALKBH3 antibody, Alkbh3 antibody
- 背景
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The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1519 AB042029.1 2-1520
Alias Symbols: ABH3, DEPC-1, DEPC1, MGC118790, MGC118792, MGC118793, PCA1
Protein Interaction Partner: AK8, LNX1, GLRX3, IKZF1, GOLGA2, SRPK2, SRPK1,
Protein Size: 286 - 分子量
- 33 kDa
- 基因ID
- 221120
- NCBI登录号
- NM_139178, NP_631917
- UniProt
- Q96Q83
- 途径
- DNA Damage Repair
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