K-RAS 抗体 (N-Term)
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- 抗原 See all K-RAS (KRAS) 抗体
- K-RAS (KRAS) (GTPase Kras (KRAS))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, 马, 豚鼠, Cow, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This K-RAS antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TEYKLVVVGA GGVGKSALTI QLIQNHFVDE YDPTIEDSYR KQVVIDGETC
- 特异性
- 100 % homologous to human KRAS, NRAS and HRAS.
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KRAS. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KRAS
- Top Product
- Discover our top product KRAS Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 189 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 别名
- KRAS (KRAS 产品)
- 物质类
- Viral Protein
- 背景
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KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Alias Symbols: C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Protein Interaction Partner: RBPMS, UBC, PSMA3, ARAF, MDFI, TRAF6, BCL2, BTRC, RAF1, MAPK1, PHB, DDX50, EGLN1, DDX47, RALGDS, RGL2, PIK3R2, LPAR1, ADH6, APP, ELAVL1, CALM1, IGSF21, CCT7, PDE4DIP, DNAJA3, EEF1A1, RASGRF2, RASSF2, RAP1GDS1, RASGRP2, RASSF5, SHOC2, PGGT1B, PIK3CG, EPB42
Protein Size: 189 - 分子量
- 22 kDa
- 基因ID
- 3845
- NCBI登录号
- NM_033360, NP_203524
- UniProt
- P01111
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