RABGEF1 抗体 (N-Term)
-
- 抗原 See all RABGEF1 抗体
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 山羊, 兔, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RABGEF1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against RABGEF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1
- Top Product
- Discover our top product RABGEF1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 491 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- 别名
- RABGEF1 (RABGEF1 产品)
- 别名
- Rab5ef antibody, Rabex5 antibody, Rin2 antibody, RABEX5 antibody, rabex-5 antibody, rabgef1 antibody, RAB guanine nucleotide exchange factor (GEF) 1 antibody, RAB guanine nucleotide exchange factor 1 antibody, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog antibody, Rabgef1 antibody, RABGEF1 antibody, rabgef1.L antibody
- 背景
-
RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
Alias Symbols: FLJ32302, RABEX5, rabex-5
Protein Interaction Partner: TRIM15, CIPC, ZC2HC1C, TRIM54, RABGEF1, BLOC1S6, TXN2, THOC1, DAZAP2, UBC, TEAD4, RABEP1, DGCR6, TNKS1BP1, ROCK2, SLMAP, MON1A, RNF11, MON1B, RAB21, UBE2D3, UBE2D1, RAB5A, L1CAM, EEA1, ESR1, EGFR, RAB22A, GGA1, MAPK1, HRAS, YWHAG, YWHAB, KXD1, GGA2, RNF16
Protein Size: 491 - 分子量
- 57 kDa
- 基因ID
- 27342
- NCBI登录号
- NM_014504, NP_055319
- UniProt
- A8K3R3
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-