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INPP5B 抗体 (Middle Region)

INPP5B 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785875
发货至: 中国
  • 抗原 See all INPP5B 抗体
    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
    抗原表位
    • 9
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 犬, 兔, 马, 豚鼠
    宿主
    • 34
    • 2
    克隆类型
    • 36
    多克隆
    标记
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INPP5B antibody is un-conjugated
    应用范围
    • 23
    • 18
    • 17
    • 14
    • 5
    • 2
    • 1
    Western Blotting (WB)
    序列
    IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN
    预测反应
    Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against INPP5B. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human INPP5B
    Top Product
    Discover our top product INPP5B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 913 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: "FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).

  • 抗原
    INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
    别名
    INPP5B (INPP5B 产品)
    别名
    75kDa antibody, AW260155 antibody, INPP5P antibody, 5PTase antibody, inositol polyphosphate-5-phosphatase B antibody, type II inositol 1,4,5-trisphosphate 5-phosphatase-like antibody, inositol polyphosphate-5-phosphatase B L homeolog antibody, inositol polyphosphate 5-phosphatase OCRL-1 antibody, INPP5B antibody, LOC100224437 antibody, inpp5b.L antibody, LOC100159919 antibody, Inpp5b antibody
    背景
    Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: 5PTase, MGC65156, MGC71303
    Protein Interaction Partner: UBC, APP, SMURF1,
    Protein Size: 913
    分子量
    77 kDa
    基因ID
    3633
    NCBI登录号
    NM_005540, NP_005531
    UniProt
    P32019
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