INPP5B 抗体 (Middle Region)
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- 抗原 See all INPP5B 抗体
- INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 犬, 兔, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INPP5B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN
- 预测反应
- Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against INPP5B. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human INPP5B
- Top Product
- Discover our top product INPP5B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 913 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).
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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress." in: Cell, Vol. 128, Issue 2, pp. 325-39, (2007) (PubMed).
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- 抗原
- INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
- 别名
- INPP5B (INPP5B 产品)
- 别名
- 75kDa antibody, AW260155 antibody, INPP5P antibody, 5PTase antibody, inositol polyphosphate-5-phosphatase B antibody, type II inositol 1,4,5-trisphosphate 5-phosphatase-like antibody, inositol polyphosphate-5-phosphatase B L homeolog antibody, inositol polyphosphate 5-phosphatase OCRL-1 antibody, INPP5B antibody, LOC100224437 antibody, inpp5b.L antibody, LOC100159919 antibody, Inpp5b antibody
- 背景
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Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: 5PTase, MGC65156, MGC71303
Protein Interaction Partner: UBC, APP, SMURF1,
Protein Size: 913 - 分子量
- 77 kDa
- 基因ID
- 3633
- NCBI登录号
- NM_005540, NP_005531
- UniProt
- P32019
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