GRF2 抗体 (C-Term)
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- 抗原 See all GRF2 (RAPGEF1) 抗体
- GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RAPGEF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RAPGEF1
- Top Product
- Discover our top product RAPGEF1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1077 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
- 别名
- RAPGEF1 (RAPGEF1 产品)
- 别名
- C3G antibody, GRF2 antibody, Link-GEFII antibody, 4932418O06Rik antibody, Grf2 antibody, RAPGEF1 antibody, C3G-1 antibody, C3G-2 antibody, C3g antibody, rapgef1 antibody, zgc:56372 antibody, Rap guanine nucleotide exchange factor 1 antibody, Rap guanine nucleotide exchange factor like 1 antibody, Rap guanine nucleotide exchange factor (GEF) 1 antibody, Rap guanine nucleotide exchange factor 1 S homeolog antibody, Rap guanine nucleotide exchange factor (GEF) 1b antibody, RAPGEF1 antibody, RAPGEFL1 antibody, Rapgef1 antibody, rapgef1.S antibody, rapgef1 antibody, rapgef1b antibody, Rapgefl1 antibody
- 背景
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RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Alias Symbols: C3G, DKFZp781P1719, GRF2
Protein Interaction Partner: UBC, MBIP, SLC20A1, ATXN1, RPS15, CRKL, CRK, CBL, GRB2, NEDD9, RHOQ, BCAR1, SHC1, RRAS2, HRAS, RAP1B, HCK, RAP1A,
Protein Size: 1077 - 分子量
- 120 kDa
- 基因ID
- 2889
- NCBI登录号
- NM_005312, NP_005303
- UniProt
- Q13905
- 途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
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