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ETF1 抗体 (N-Term)

ETF1 适用: 人, 小鼠, 大鼠, 豚鼠, 斑马鱼, 马, Cow, 犬, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785859
发货至: 中国
  • 抗原 See all ETF1 抗体
    ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 16
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 豚鼠, 斑马鱼, 马, Cow, 犬, 兔, Saccharomyces cerevisiae
    宿主
    • 14
    • 3
    克隆类型
    • 14
    • 3
    多克隆
    标记
    • 17
    This ETF1 antibody is un-conjugated
    应用范围
    • 14
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ISLIIPPKDQ ISRVAKMLAD EFGTASNIKS RVNRLSVLGA ITSVQQRLKL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against ETF1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ETF1
    Top Product
    Discover our top product ETF1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 437 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
    别名
    ETF1 (ETF1 产品)
    背景
    Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA, however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons (Frolova et al., 1994 [PubMed 7990965]).
    Alias Symbols: D5S1995, ERF, ERF1, MGC111066, RF1, SUP45L1, TB3-1
    Protein Interaction Partner: KEAP1, UBC, RTF1, NUDC, VPS26A, TSN, CORO1C, CORO1B, HECW2, ALB, UPF1, LIG4, GSPT1, PPP2CA, GSPT2, PABPC1,
    Protein Size: 437
    分子量
    49 kDa
    基因ID
    2107
    NCBI登录号
    NM_004730, NP_004721
    UniProt
    P62495
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