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KPNA1 抗体 (N-Term)

KPNA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785822
发货至: 中国
  • 抗原 See all KPNA1 抗体
    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
    抗原表位
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 36
    • 17
    • 16
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 26
    • 8
    • 1
    • 1
    克隆类型
    • 30
    • 6
    多克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA1 antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    TTPGKENFRL KSYKNKSLNP DEMRRRREEE GLQLRKQKRE EQLFKRRNVA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against KPNA1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA1
    Top Product
    Discover our top product KPNA1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 538 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Theodore, Kawai, Yang, Kleshchenko, Reddy, Villalta, Arinze: "Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 8984-94, (2008) (PubMed).

  • 抗原
    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
    别名
    KPNA1 (KPNA1 产品)
    别名
    IPOA5 antibody, NPI-1 antibody, RCH2 antibody, SRP1 antibody, AW494490 antibody, NPI1 antibody, Rch2 antibody, mSRP1 antibody, si:ch211-161h7.7 antibody, karyopherin subunit alpha 1 antibody, importin alpha-1 subunit antibody, karyopherin (importin) alpha 1 antibody, karyopherin alpha 1 (importin alpha 5) antibody, KPNA1 antibody, Kpna1 antibody, EHI_124900 antibody, kpna1 antibody
    背景
    Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V(D)J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: IPOA5, NPI-1, RCH2, SRP1
    Protein Interaction Partner: UBC, TAF9, CLK4, NUP50, ANP32B, XRN2, rev, TRMT61A, KCTD12, NPM1, GABPA, DCAF6, LIMCH1, HECW2, CLK3, HDAC2, HDAC1, GOPC, HDAC6, CRADD, LMO4, BCAR3, FOSL1, SKP2, ORC4, IL1RAP, AICDA, TP53BP1, KPNB1, RAG1, NOSIP, DCAF8, ANP32A, CAND1, COPS5, CUL1, CUL3, CUL
    Protein Size: 538
    分子量
    60 kDa
    基因ID
    3836
    NCBI登录号
    NM_002264, NP_002255
    UniProt
    P52294
    途径
    M Phase, Protein targeting to Nucleus
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