GALE 抗体 (Middle Region)
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- 抗原 See all GALE 抗体
- GALE (UDP-Galactose-4-Epimerase (GALE))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 犬, Cow, Pig, 兔, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GALE antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PQGIPNNLMP YVSQVAIGRR EALNVFGNDY DTEDGTGVRD YIHVVDLAKG
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against GALE. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GALE
- Top Product
- Discover our top product GALE Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 348 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GALE (UDP-Galactose-4-Epimerase (GALE))
- 别名
- GALE (GALE 产品)
- 别名
- GALE antibody, im:7147391 antibody, wu:fb05f01 antibody, zgc:136578 antibody, F15H21.11 antibody, F15H21_11 antibody, REB1 antibody, ROOT EPIDERMAL BULGER1 antibody, ROOT HAIR DEFECTIVE 1 antibody, UDP-GLUCOSE 4-EPIMERASE antibody, UGE4 antibody, ECK0748 antibody, galD antibody, JW0742 antibody, SMU.888 antibody, BA5505 antibody, BA5700 antibody, VFA0352 antibody, galE antibody, 2310002A12Rik antibody, AI323962 antibody, 1n569 antibody, xgale antibody, SDR1E1 antibody, UDP-galactose-4-epimerase antibody, NAD(P)-binding Rossmann-fold superfamily protein antibody, UDP-galactose 4-epimerase GalE antibody, UDP-glucose 4-epimerase antibody, UDP-glucose 4-epimerase GalE antibody, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase antibody, galactose-4-epimerase, UDP antibody, UDP-galactose-4-epimerase L homeolog antibody, GALE antibody, gale antibody, RHD1 antibody, ECs0787 antibody, galE antibody, galE1 antibody, galE2 antibody, STY0809 antibody, galE-2 antibody, SG0897 antibody, galD antibody, Ent638_1250 antibody, Gale antibody, gale.L antibody
- 背景
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GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
Alias Symbols: SDR1E1
Protein Interaction Partner: GALE, SUMO2, UBC, BAG3, FN1, APP,
Protein Size: 348 - 分子量
- 38 kDa
- 基因ID
- 2582
- NCBI登录号
- NM_001008216, NP_001008217
- UniProt
- Q14376
- 途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
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