Gelsolin 抗体 (C-Term)
-
- 抗原 See all Gelsolin (GSN) 抗体
- Gelsolin (GSN)
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 小鼠, Cow, 兔, 犬, 马, 绵羊, 斑马鱼, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Gelsolin antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KPMIIYKGGT SREGGQTAPA STRLFQVRAN SAGATRAVEV LPKAGALNSN
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against GSN. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GSN
- Top Product
- Discover our top product GSN Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 782 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Ardalan-Shoja-Kiuru syndrome--hereditary gelsolin amyloidosis plus retinitis pigmentosa." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 23, Issue 3, pp. 1071; author reply 1071-2, (2008) (PubMed).
: "
-
Ardalan-Shoja-Kiuru syndrome--hereditary gelsolin amyloidosis plus retinitis pigmentosa." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 23, Issue 3, pp. 1071; author reply 1071-2, (2008) (PubMed).
-
- 抗原
- Gelsolin (GSN)
- 别名
- GSN (GSN 产品)
- 别名
- ADF antibody, AGEL antibody, CG1106 antibody, DGS antibody, Dmel\\CG1106 antibody, gel antibody, scin antibody, cb107 antibody, gsn antibody, sb:cb107 antibody, u-gelsolin antibody, wu:fi16f06 antibody, gelsolin antibody, Gelsolin antibody, gelsolin S homeolog antibody, gelsolin a antibody, GSN antibody, Gel antibody, Gsn antibody, gsn.S antibody, gsn antibody, gsna antibody
- 背景
-
GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: DKFZp313L0718, ADF, AGEL
Protein Interaction Partner: ITCH, CFLAR, TP53, UBC, CASP3, UBD, FN1, MPG, ESR1, ALB, SDHB, ACTA1, MDM2, UBE2Q2, FBXO25, ARRB2, ARRB1, AR, PSMD4, TNIK, CLIC5, TOM1L1, ACTN4, VDAC1, BCAR1, PXN, LIMK2, VASP, PIK3CG, PTK2B, FHIT, VCL, CSK, APP, ACTB, ACTG1, PLCG1, SRC, PTPN12, PTK2, PIK
Protein Size: 782 - 分子量
- 83 kDa
- 基因ID
- 2934
- NCBI登录号
- NM_000177, NP_000168
- UniProt
- P06396
- 途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
-