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- 抗原 See all ACRV1 抗体
- ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))
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抗原表位
- N-Term
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适用
- 人, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACRV1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MNRFLLLMSL YLLGSARGTS SQPNELSGSI DHQTSVQQLP GEFFSLENPS
- 预测反应
- Guinea Pig: 79%, Human: 100%, Rabbit: 85%
- 产品特性
- This is a rabbit polyclonal antibody against ACRV1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACRV1
- Top Product
- Discover our top product ACRV1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 265 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10." in: Journal of reproductive immunology, Vol. 53, Issue 1-2, pp. 25-36, (2001) (PubMed).
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Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10." in: Journal of reproductive immunology, Vol. 53, Issue 1-2, pp. 25-36, (2001) (PubMed).
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- 抗原
- ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))
- 别名
- ACRV1 (ACRV1 产品)
- 别名
- ACRV1 antibody, D11S4365 antibody, SP-10 antibody, SPACA2 antibody, Msa63 antibody, Sp10 antibody, acrosomal vesicle protein 1 antibody, ACRV1 antibody, Acrv1 antibody
- 背景
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ACRV1 is a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72 % of the total acrosomal vesicle protein 1 messages, the second largest transcript comprises 15-32 %, the third and the fourth largest transcripts account for 3.4-8.3 % and 8.7-12.5 %, respectively, and the remaining transcripts combined account for < 1 % of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
Alias Symbols: D11S4365, SP-10, SPACA2
Protein Size: 265 - 分子量
- 29 kDa
- 基因ID
- 56
- NCBI登录号
- NM_001612, NP_001603
- UniProt
- P26436
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