STAMBP 抗体 (N-Term)
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- 抗原 See all STAMBP 抗体
- STAMBP (STAM Binding Protein (STAMBP))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAMBP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SDHGDVSLPP EDRVRALSQL GSAVEVNEDI PPRRYFRSGV EIIRMASIYS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against STAMBP. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human STAMBP
- Top Product
- Discover our top product STAMBP Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 424 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- STAMBP (STAM Binding Protein (STAMBP))
- 别名
- STAMBP (STAMBP 产品)
- 背景
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Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: AMSH, MGC126516, MGC126518
Protein Interaction Partner: CHMP1B, CHMP3, GRB2, UBC, TNFRSF1A, GJA1, MAP3K2, VAMP8, SUMO1, NEDD8, CLTC, FDPS, STAM, STAM2, GRAP2, TRIP13, SPG7, CHMP1A, ITGA5, CYP2C9, NTPCR, CHMP5, SMAD7, SMAD6, PJA1, USP28, USP21, CHMP4B, AMN, CTNNBL1, UACA, CHMP4A, MAP2K5, ALAS1, CASR, UBE2S, TRA
Protein Size: 424 - 分子量
- 48 kDa
- 基因ID
- 10617
- NCBI登录号
- NM_213622, NP_998787
- UniProt
- O95630
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