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H1FOO 抗体 (N-Term)

H1FOO 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785287
发货至: 中国
  • 抗原 See all H1FOO 抗体
    H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term
    适用
    • 30
    • 18
    • 3
    • 2
    人, 大鼠
    宿主
    • 45
    • 2
    克隆类型
    • 47
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This H1FOO antibody is un-conjugated
    应用范围
    • 23
    • 23
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    MAPGSVTSDI SPSSTSTAGS SRSPESEKPG PSHGGVPPGG PSHSSLPVGR
    预测反应
    Human: 100%, Rat: 83%
    产品特性
    This is a rabbit polyclonal antibody against H1FOO. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human H1FOO
    Top Product
    Discover our top product H1FOO Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 346 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hongo, Noguchi, Okuyama, Tanaka, Nishino: "Repetitive interactions observed in the crystal structure of a collagen-model peptide, [(Pro-Pro-Gly)9]3." in: Journal of biochemistry, Vol. 138, Issue 2, pp. 135-44, (2005) (PubMed).

    Tanaka, Kihara, Hennebold, Eppig, Viveiros, Emery, Carrell, Kirkman, Meczekalski, Zhou, Bondy, Becker, Schultz, Misteli, De La Fuente, King, Adashi: "H1FOO is coupled to the initiation of oocytic growth." in: Biology of reproduction, Vol. 72, Issue 1, pp. 135-42, (2004) (PubMed).

  • 抗原
    H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))
    别名
    H1FOO (H1FOO 产品)
    别名
    osH1 antibody, C86609 antibody, H1fo antibody, H1oo antibody, b4 antibody, RGD1566236 antibody, H1 histone family member O oocyte specific antibody, H1 histone family, member O, oocyte-specific antibody, H1 histone family member O oocyte specific S homeolog antibody, H1FOO antibody, H1foo antibody, h1foo.S antibody
    背景
    H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.
    Alias Symbols: MGC50807, osH1
    Protein Size: 346
    分子量
    36 kDa
    基因ID
    132243
    NCBI登录号
    NM_153833, NP_722575
    UniProt
    Q8IZA3
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