KHDRBS2 抗体 (N-Term)
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- 抗原 See all KHDRBS2 抗体
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KHDRBS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EEIEKFQGSD GKKEDEEKKY LDVISNKNIK LSERVLIPVK QYPKFNFVGK
- 预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KHDRBS2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS2
- Top Product
- Discover our top product KHDRBS2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 349 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))
- 别名
- KHDRBS2 (KHDRBS2 产品)
- 别名
- slm1 antibody, slm-1 antibody, MGC145973 antibody, ba535f17.1 antibody, zgc:153588 antibody, SLM-1 antibody, SLM1 antibody, bA535F17.1 antibody, 6330586C16Rik antibody, Slim1 antibody, Slm1 antibody, KH RNA binding domain containing, signal transduction associated 2 antibody, KH domain containing, RNA binding, signal transduction associated 2 antibody, KHDRBS2 antibody, khdrbs2 antibody, Khdrbs2 antibody
- 背景
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KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Alias Symbols: FLJ38664, MGC26664, SLM-1, SLM1, bA535F17.1
Protein Interaction Partner: HBZ, DOCK2, CIRBP, TYMSOS, LINC01018, KHDRBS2, ZFC3H1, CATSPER1, YTHDC1, PRR3, NABP1, AEN, NCOA5, NPDC1, RBMX, PRPF31, CHTOP, HNRNPR, MTA1, TYK2, SULT1A3, SPG7, SDCBP, RBM3, PTK6, UBC, KHDRBS3, HNRNPK, LYN, HNRNPC, HNRNPA2B1, HNRNPA1, FGG, FGB, FGA, DSG1,
Protein Size: 349 - 分子量
- 39 kDa
- 基因ID
- 202559
- NCBI登录号
- NM_152688, NP_689901
- UniProt
- Q5VWX1
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