Crossover junction endonuclease EME1 (EME1) (Middle Region) 抗体
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- 抗原 See all Crossover junction endonuclease EME1 (EME1) 抗体
- Crossover junction endonuclease EME1 (EME1)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Pig, 兔, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 序列
- AYPSPQLLVQ AYQQCFSDKE RQNLLADIQV RRGEGVTSTS RRIGPELSRR
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against EME1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human EME1
- Top Product
- Discover our top product EME1 Primary Antibody
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anti-Crossover junction endonuclease EME1 (EME1) (AA 1-583) antibody
EME1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (AA 1-583) antibodyEME1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (Internal Region) antibodyEME1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (AA 520-561), (C-Term) antibodyEME1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) antibodyEME1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (N-Term) antibodyEME1 适用: 人, 小鼠, Pig, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (C-Term) antibodyEME1 适用: 人, 小鼠, Pig, 兔, 犬, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (AA 1-320) antibodyEME1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Crossover junction endonuclease EME1 (EME1) (Internal Region) antibodyEME1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 570 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Crossover junction endonuclease EME1 (EME1)
- 别名
- EME1 (EME1 产品)
- 背景
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EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM].
Alias Symbols: FLJ31364, MMS4L, SLX2A
Protein Interaction Partner: vpr, MUS81, APP, SLX1A, EME1, SLX4, SUMO2, SLX1B,
Protein Size: 570 - 分子量
- 63 kDa
- 基因ID
- 146956
- NCBI登录号
- NM_152463, NP_689676
- UniProt
- Q96AY2
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