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MTPN 抗体 (Middle Region)

MTPN 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785128
发货至: 中国
  • 抗原 See all MTPN 抗体
    MTPN (Myotrophin (MTPN))
    抗原表位
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 24
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 21
    • 4
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTPN antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    GRKPLHYAAD CGQLEILEFL LLKGADINAP DKHHITPLLS AVYEGHVSCV
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against MTPN. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MTPN
    Top Product
    Discover our top product MTPN Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 118 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Nghiem, Hoffman, Mittal, Brown, Schatzberg, Ghimbovschi, Wang, Kornegay: "Sparing of the dystrophin-deficient cranial sartorius muscle is associated with classical and novel hypertrophy pathways in GRMD dogs." in: The American journal of pathology, Vol. 183, Issue 5, pp. 1411-24, (2013) (PubMed).

  • 抗原
    MTPN (Myotrophin (MTPN))
    别名
    MTPN (MTPN 产品)
    别名
    MGC76285 antibody, GCDP antibody, V-1 antibody, Gcdp antibody, wu:fa10f07 antibody, zgc:64078 antibody, 5033418D15Rik antibody, V1 antibody, myotrophin antibody, myotrophin S homeolog antibody, mtpn antibody, MTPN antibody, Mtpn antibody, mtpn.S antibody
    背景
    MTPN has a potential role in cerebellar morphogenesis. MTPN may function in differentiation of cerebellar neurons, particularly of granule cells. MTPN seems to be associated with cardiac hypertrophy.The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
    Alias Symbols: FLJ31098, GCDP, V-1
    Protein Interaction Partner: RBBP4, RAB1A, PTPN11, OXCT1, MTAP, PDIA3, ATP6V1A, UBC, NPLOC4, ELAVL1, MAPK1, CAPZB, RELA, NFKB1, REL, DSTYK,
    Protein Size: 118
    分子量
    13 kDa
    基因ID
    136319
    NCBI登录号
    NM_145808, NP_665807
    UniProt
    P58546
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