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- 抗原 See all CAPN10 抗体
- CAPN10 (Calpain 10 (CAPN10))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 犬, 兔, 豚鼠, 大鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAPN10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MRAGRGATPA RELFRDAAFP AADSSLFCDL STPLAQFRED ITWRRPQEIC
- 预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CAPN10. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAPN10
- Top Product
- Discover our top product CAPN10 Primary Antibody
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anti-Calpain 10 (CAPN10) (AA 1-672) antibody
CAPN10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (N-Term) antibodyCAPN10 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (N-Term) antibodyCAPN10 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (AA 44-93) antibodyCAPN10 适用: 人, 小鼠, 犬, 兔, 豚鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (N-Term) antibodyCAPN10 适用: 人, 犬, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (AA 1-230) antibodyCAPN10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calpain 10 (CAPN10) (AA 22-374) antibodyCAPN10 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 517 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CAPN10 (Calpain 10 (CAPN10))
- 别名
- CAPN10 (CAPN10 产品)
- 别名
- CAPN10 antibody, CANP10 antibody, NIDDM1 antibody, AW049679 antibody, Capn8 antibody, mKIAA1845 antibody, calpain 10 antibody, calpain 10 L homeolog antibody, CAPN10 antibody, capn10.L antibody, capn10 antibody, Capn10 antibody
- 背景
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CAPN10 is the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: CANP10, NIDDM1
Protein Interaction Partner: EFNB1, FLOT1, PSMA7, FANCC,
Protein Size: 517 - 分子量
- 58 kDa
- 基因ID
- 11132
- NCBI登录号
- NM_023085, NP_075573
- UniProt
- Q9HC96
- 途径
- Positive Regulation of Peptide Hormone Secretion
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