COPB1 抗体 (Middle Region)
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- 抗原 See all COPB1 抗体
- COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QLALDLVSSR NVEELVIVLK KEVIKTNNVS EHEDTDKYRQ LLVRTLHSCS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against COPB1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human COPB1
- Top Product
- Discover our top product COPB1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 953 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, (2007) (PubMed).
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Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, (2007) (PubMed).
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- 抗原
- COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
- 别名
- COPB1 (COPB1 产品)
- 别名
- id:ibd5034 antibody, wu:fc66c05 antibody, zgc:92482 antibody, COPB1 antibody, DKFZp459K154 antibody, COPB antibody, 2610019B04Rik antibody, Rack2 antibody, Beta-COP antibody, coatomer protein complex, subunit beta 1 antibody, coatomer protein complex subunit beta 1 L homeolog antibody, coatomer protein complex subunit beta 1 antibody, copb1 antibody, copb1.L antibody, COPB1 antibody, Copb1 antibody
- 背景
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The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPB, DKFZp761K102, FLJ10341
Protein Interaction Partner: SUMO2, NUDCD1, UBC, RNF2, EZH2, KLC1, DIAPH1, ARCN1, ACACA, COPG1, COPZ1, TLE3, FBXO6, UBD, KCNK3, KCNK9, NPM1, HDAC10, ERBB2IP, SNTA1, LZTS2, VPS18, NUB1, SERTAD1, FOXB1, IRAK3, TANK, ID1, HLA-DPB1, GRB2, XRCC6, FN1, CFTR, FMNL1, COPG2, COPE, COPB2, COPA
Protein Size: 953 - 分子量
- 107 kDa
- 基因ID
- 1315
- NCBI登录号
- NM_016451, NP_057535
- UniProt
- P53618
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