Peroxiredoxin 3 抗体 (N-Term)
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- 抗原 See all Peroxiredoxin 3 (PRDX3) 抗体
- Peroxiredoxin 3 (PRDX3)
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Peroxiredoxin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AIPWGISATA ALRPAACGRT SLTNLLCSGS SQAPYFKGTA VVNGEFKDLS
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PRDX3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX3
- Top Product
- Discover our top product PRDX3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 238 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Peroxiredoxin 3 (PRDX3)
- 别名
- PRDX3 (PRDX3 产品)
- 背景
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PRDX3 is a protein with antioxidant function and is localized in the mitochondrion. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: AOP-1, AOP1, MER5, MGC104387, MGC24293, PRO1748, SP-22, HBC189, prx-III
Protein Interaction Partner: GORASP2, SUMO1, NEDD8, MDM2, ARMCX3, NUSAP1, LNPEP, HNRNPD, NEK6, CDK2, UBC, TNFRSF1A, ITGA4, FN1, RPS6KC1, PRDX3, PRDX4, VCAM1, RNASET2, PSME1, PFKL, SPEN, UBQLN4, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, SUMO4, MAPK3, NLRX1, HDAC5, UCHL5, H2AFX, T
Protein Size: 238 - 分子量
- 26 kDa
- 基因ID
- 10935
- NCBI登录号
- NM_014098, NP_054817
- UniProt
- P30048
- 途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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