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Dynamin 1-Like 抗体 (N-Term)

DNM1L 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784887
发货至: 中国
  • 抗原 See all Dynamin 1-Like (DNM1L) 抗体
    Dynamin 1-Like (DNM1L)
    抗原表位
    • 23
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 50
    • 43
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼
    宿主
    • 58
    • 7
    克隆类型
    • 58
    • 7
    多克隆
    标记
    • 31
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynamin 1-Like antibody is un-conjugated
    应用范围
    • 32
    • 28
    • 17
    • 13
    • 13
    • 11
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    IRQEIENETE RISGNNKGVS PEPIHLKIFS PNVVNLTLVD LPGMTKVPVG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against DNM1L. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L
    Top Product
    Discover our top product DNM1L Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 736 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Su, Chiu, Hung, Hong: "Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 10, pp. 1457-70, (2014) (PubMed).

  • 抗原
    Dynamin 1-Like (DNM1L)
    别名
    DNM1L (DNM1L 产品)
    背景
    The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
    Alias Symbols: DLP1, DRP1, DVLP, DYMPLE, HDYNIV, VPS1, EMPF, DYNIV-11
    Protein Interaction Partner: ZBTB24, UBC, SCG3, SH3GL1, RRM2, MAGEA3, MAGEA1, MARCH5, EGFR, VPS26A, SSB, CARS, ATP6V1C1, APEH, PSMG3, FAM129B, TBC1D15, CYHR1, ARFIP1, JMJD6, SEC24A, SOX2, DNM1L, MIEF2, MFF, PEX14, LRRK2, MIEF1, COPS5, GABRR1, MUL1, SUMO2, PARK2, PEX25, PEX11G, PEX11A
    Protein Size: 736
    分子量
    82 kDa
    基因ID
    10059
    NCBI登录号
    NM_012062, NP_036192
    UniProt
    O00429
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