PADI2 抗体 (Middle Region)
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- 抗原 See all PADI2 抗体
- PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 斑马鱼, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PADI2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RGDRWIQDEI EFGYIEAPHK GFPVVLDSPR DGNLKDFPVK ELLGPDFGYV
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 83%
- 产品特性
- This is a rabbit polyclonal antibody against PADI2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PADI2
- Top Product
- Discover our top product PADI2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 665 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PADI2 (Peptidyl Arginine Deiminase, Type II (PADI2))
- 别名
- PADI2 (PADI2 产品)
- 别名
- PADI2 antibody, PAD-H19 antibody, PAD2 antibody, PDI2 antibody, Pdi antibody, Pdi2 antibody, mKIAA0994 antibody, peptidyl arginine deiminase 2 antibody, peptidyl arginine deiminase, type II antibody, protein-arginine deiminase type-2 antibody, peptidyl arginine deiminase, type II S homeolog antibody, PADI2 antibody, padi2 antibody, LOC100357368 antibody, padi2.S antibody, Padi2 antibody
- 背景
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PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. PADI2 is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KIAA0994, PAD-H19, PAD2, PDI2
Protein Interaction Partner: UBC,
Protein Size: 665 - 分子量
- 75 kDa
- 基因ID
- 11240
- NCBI登录号
- NM_007365, NP_031391
- UniProt
- Q9Y2J8
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