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METAP2 抗体 (N-Term)

METAP2 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784850
发货至: 中国
  • 抗原 See all METAP2 抗体
    METAP2 (Methionyl Aminopeptidase 2 (METAP2))
    抗原表位
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 64
    • 14
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔
    宿主
    • 59
    • 4
    • 1
    克隆类型
    • 53
    • 11
    多克隆
    标记
    • 27
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This METAP2 antibody is un-conjugated
    应用范围
    • 44
    • 33
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ATGKKKKKKK KKRGPKVQTD PPSVPICDLY PNGVFPKGQE CEYPPTQDGR
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against METAP2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human METAP2
    Top Product
    Discover our top product METAP2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 478 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    METAP2 (Methionyl Aminopeptidase 2 (METAP2))
    别名
    METAP2 (METAP2 产品)
    别名
    metap2 antibody, MGC53792 antibody, METAP2 antibody, GB13458 antibody, DDBDRAFT_0190923 antibody, DDBDRAFT_0304991 antibody, DDB_0190923 antibody, DDB_0304991 antibody, 4930584B20Rik antibody, A930035J23Rik antibody, AI047573 antibody, AL024412 antibody, AU014659 antibody, Amp2 antibody, Mnpep antibody, p67 antibody, p67eIF2 antibody, MAP2 antibody, MNPEP antibody, wu:fb98h06 antibody, zgc:66250 antibody, methionyl aminopeptidase 2 L homeolog antibody, methionyl aminopeptidase 2 antibody, methionine aminopeptidase 2 antibody, methionine aminopeptidase antibody, methionyl aminopeptidase 2 S homeolog antibody, methionyl aminopeptidase 2b antibody, metap2.L antibody, METAP2 antibody, metap2 antibody, LOC551771 antibody, CAALFM_C604080WA antibody, Metap2 antibody, metap2.S antibody, metap2b antibody
    背景
    METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MAP2, MNPEP, p67, p67eIF2
    Protein Interaction Partner: UBC, DAK, NPEPPS, GBP1, GAPDH, HMGA1, MTOR, EEF2K, APP, CALM1, S100A4, RAC1, MAPK3, EIF2S3, MAPK1, EIF2AK2, CDC42, E2F4,
    Protein Size: 478
    分子量
    53 kDa
    基因ID
    10988
    NCBI登录号
    NM_006838, NP_006829
    UniProt
    P50579
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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