RALBP1 抗体 (N-Term)
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- 抗原 See all RALBP1 抗体
- RALBP1 (RalA Binding Protein 1 (RALBP1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, Pig, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RALBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RALBP1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RALBP1
- Top Product
- Discover our top product RALBP1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 655 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RALBP1 (RalA Binding Protein 1 (RALBP1))
- 别名
- RALBP1 (RALBP1 产品)
- 背景
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RALBP1 can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RALBP1 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. RALBP1 serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Alias Symbols: RIP, RIP1, RLIP76, RLIP1
Protein Interaction Partner: TNIP1, CEP57, SMARCE1, PPL, GPS2, GSE1, ZNF707, ZBTB38, C1orf216, TBRG1, AMOTL2, TFPT, UBC, RALB, GPSM1, PRKCA, CPSF2, POLR2A, AP2A1, SYNJ2BP, HOOK2, REPS1, FADD, RAC1, TRAF2, CASP8, AP2M1, REPS2, IKBKG, RALA, CCNB1, HSP90AA1, HSF1, EPN1, NUMB, GTF3A, TNF
Protein Size: 655 - 分子量
- 76 kDa
- 基因ID
- 10928
- NCBI登录号
- NM_006788, NP_006779
- UniProt
- Q15311
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