COPS8 抗体 (Middle Region)
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- 抗原 See all COPS8 抗体
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, 马, 兔, Cow, 豚鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TRMVLPRKPV AGALDVSFNK FIPLSEPAPV PPIPNEQQLA RLTDYVAFLE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against COPS8. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human COPS8
- Top Product
- Discover our top product COPS8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 209 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).
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The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).
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- 抗原
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- 别名
- COPS8 (COPS8 产品)
- 别名
- COP9 antibody, CSN8 antibody, SGN8 antibody, csn8 antibody, cops8 antibody, MGC76051 antibody, MGC80215 antibody, DDBDRAFT_0167123 antibody, DDBDRAFT_0233107 antibody, DDB_0167123 antibody, DDB_0233107 antibody, zgc:56319 antibody, zgc:86840 antibody, MGC86182 antibody, 9430009J09Rik antibody, AA408242 antibody, Csn8 antibody, Sgn8 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 9 antibody, COP9 SIGNALOSOME SUBUNIT 8 antibody, DL3095C antibody, EMB143 antibody, EMBRYO DEFECTIVE 143 antibody, FCAALL.131 antibody, FUS7 antibody, FUSCA 7 antibody, FUSCA PROTEIN FUS7 antibody, CG13383 antibody, CG33297 antibody, CG42522 antibody, CH8 antibody, Dch8 antibody, Dmel\\CG42522 antibody, Dmel_CG13383 antibody, l(2)SH1829 antibody, l(2)SH2 1829 antibody, COP9 signalosome subunit 8 antibody, COP9 signalosome subunit 8 S homeolog antibody, COP9 signalosome complex subunit 8 antibody, COP9 signalosome subunit 8 L homeolog antibody, COP9 signalosome, subunit CSN8 antibody, COPS8 antibody, Cops8 antibody, cops8 antibody, cops8.S antibody, CSN8 antibody, csn8 antibody, cops8.L antibody, COP9 antibody
- 背景
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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: COP9, CSN8, MGC1297, MGC43256, SGN8
Protein Interaction Partner: USHBP1, GPS1, cul1, WDR77, SRRT, COPS7A, VIM, COPS4, FBXO6, FBXW4, COPS5, vpr, IRF5, DDIT3, COPS2, COPS3, COPS6, PINK1, RFWD2, CUL4A, UBC, LRR1, DDA1, DDB2, DCUN1D1, VPRBP, CUL2, CUL3, CUL4B, CUL5, NEDD8, JUN, GFER, ERCC8, DDB1, CTNNB1, RAE1, COPS8, EIF3E
Protein Size: 209 - 分子量
- 23 kDa
- 基因ID
- 10920
- NCBI登录号
- NM_006710, NP_006701
- UniProt
- Q99627
- 途径
- Cell Division Cycle
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