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TXNIP 抗体 (C-Term)

Name: TXNIP 抗体 (C-Term)
SKU: ABIN2784817
Availability: OutOfStock

TXNIP 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

Host: Rabbit Target Name: TXNIP Sample Tissue: Human Fetal Lung Antibody Dilution: 1. (TXNIP 抗体 (C-Term))

Host: Rabbit Target Name: TXNIP Sample Type: Human Adult Placenta Antibody Dilution: 1. (TXNIP 抗体 (C-Term))

Host: Rabbit Target Name: TXNIP Sample Type: Human Fetal Lung Antibody Dilution: 1. (TXNIP 抗体 (C-Term))

WB Suggested Anti-TXNIP Antibody Titration: 0. (TXNIP 抗体 (C-Term))

4 images

(1 reference)

产品编号 ABIN2784817

发货至: 中国

Datasheet as PDF

抗原 See all TXNIP 抗体

TXNIP (Thioredoxin Interacting Protein (TXNIP))
抗原表位
16

14

9

8

5

5

2

1

1

1

1

1

1

1

1

1

1
C-Term
适用
67

47

32

4

3

3

3

2

2

1

1

1
人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊
宿主
76

5
兔
Compatible Secondaries
克隆类型
68

13
多克隆
标记
30

8

7

6

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This TXNIP antibody is un-conjugated
应用范围
57

32

15

14

14

8

8

5

4

3

3

1

1
Western Blotting (WB)

序列

DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against TXNIP. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human TXNIP

Top Product

Discover our top product TXNIP Primary Antibody
anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibody
TXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibody
TXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibody
TXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibody
TXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibody
TXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 121-170) antibody
TXNIP 适用: 人, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 391 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: "Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6912-7, (2008) (PubMed).
抗原

TXNIP (Thioredoxin Interacting Protein (TXNIP))

别名

TXNIP (TXNIP 产品)

别名

EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody

背景

TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Alias Symbols: EST01027, HHCPA78, THIF, VDUP1
Protein Interaction Partner: UBC, DDIT4, ECD, TXN, TP53, SMURF2, UL49, ITCH, ELAVL1, FHL1, ZBTB32, ZBTB16, SCEL, HDAC1, TXNRD1, KPNA2,
Protein Size: 391

分子量

44 kDa

基因ID

10628

NCBI登录号

NM_006472, NP_006463

UniProt

Q9H3M7

途径

Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome