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Protein Tob1 (TOB1) (Middle Region) 抗体

TOB1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784777
发货至: 中国
  • 抗原 See all Protein Tob1 (TOB1) 抗体
    Protein Tob1 (TOB1)
    抗原表位
    • 15
    • 10
    • 10
    • 10
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 50
    • 32
    • 29
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, Pig, Saccharomyces cerevisiae
    宿主
    • 64
    • 2
    克隆类型
    • 66
    多克隆
    标记
    • 24
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 33
    • 27
    • 13
    • 13
    • 11
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT
    预测反应
    Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 92%, Yeast: 100%
    产品特性
    This is a rabbit polyclonal antibody against TOB1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human TOB1
    Top Product
    Discover our top product TOB1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 345 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Protein Tob1 (TOB1)
    别名
    TOB1 (TOB1 产品)
    别名
    Tob antibody, Trob antibody, APRO5 antibody, APRO6 antibody, PIG49 antibody, TOB antibody, TROB antibody, TROB1 antibody, tob1 antibody, tob1l antibody, wu:fb54d02 antibody, wu:fb98h12 antibody, wu:fd15f10 antibody, zgc:65837 antibody, transducer of ErbB-2.1 antibody, transducer of ERBB2, 1 antibody, transducer of ERBB2, 1a antibody, transducer of ERBB2, 1 S homeolog antibody, transducer of ERBB2, 1b antibody, Tob1 antibody, TOB1 antibody, tob1a antibody, tob1.S antibody, tob1b antibody
    背景
    This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
    Alias Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
    Protein Interaction Partner: CORO7, APP, DTL, CDC7, PABPC1, CHAF1A, PAN2, UBR5, ELAVL1, SMAD3, CTNNB1, UBC, SKP2, SCMH1, MARCKS, SETDB1, CNOT7, SMAD9, SMAD5, SMAD6, SMAD1, SMAD2, SMAD4, MAPK1, ERBB2, RPS6KA1, MAPK9,
    Protein Size: 345
    分子量
    38 kDa
    基因ID
    10140
    NCBI登录号
    NM_005749, NP_005740
    UniProt
    P50616
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