Endonuclease G 抗体 (Middle Region)
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- 抗原 See all Endonuclease G (ENDOG) 抗体
- Endonuclease G (ENDOG)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 斑马鱼, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Endonuclease G antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YVMPNAPVDE AIPLERFLVP IESIERASGL LFVPNILARA GSLKAITAGS
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ENDOG. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ENDOG
- Top Product
- Discover our top product ENDOG Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 297 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).
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Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).
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- 抗原
- Endonuclease G (ENDOG)
- 别名
- ENDOG (ENDOG 产品)
- 别名
- CG8862 antibody, Dmel\\CG8862 antibody, Tb08.10J17.140 antibody, Tb08.10J17.90 antibody, TBC1D13 antibody, endog antibody, ENDOG antibody, wu:fb79c08 antibody, zgc:110020 antibody, Endonuclease G antibody, endonuclease G antibody, putative endonuclease G antibody, endonuclease G, mitochondrial antibody, endonuclease G L homeolog antibody, EndoG antibody, Tc00.1047053506867.10 antibody, Tb927.8.4040 antibody, Tb927.8.4090 antibody, LBRM_10_0750 antibody, LMJF_10_0610 antibody, NAEGRDRAFT_78507 antibody, ENDOG antibody, endog antibody, eNDOG antibody, LOC100529218 antibody, Endog antibody, endog.L antibody
- 背景
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ENDOG cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, ENDOG also has ribonuclease (RNase) and RNase H activities. ENDOG is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Alias Symbols: FLJ27463
Protein Interaction Partner: UBC, BIRC2, DNAJA4, STUB1, HSPA4, AIFM1, FEN1,
Protein Size: 297 - 分子量
- 28 kDa
- 基因ID
- 2021
- NCBI登录号
- NM_004435, NP_004426
- UniProt
- Q14249
- 途径
- Apoptosis
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