CK1 epsilon 抗体 (N-Term)
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- 抗原 See all CK1 epsilon (CSNK1E) 抗体
- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 绵羊, 兔, 豚鼠, 马, Cow, Saccharomyces cerevisiae, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CK1 epsilon antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CSNK1E. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CSNK1E
- Top Product
- Discover our top product CSNK1E Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 416 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Genetic susceptibility to heroin addiction: a candidate gene association study." in: Genes, brain, and behavior, Vol. 7, Issue 7, pp. 720-9, (2009) (PubMed).
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Genetic susceptibility to heroin addiction: a candidate gene association study." in: Genes, brain, and behavior, Vol. 7, Issue 7, pp. 720-9, (2009) (PubMed).
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- 抗原
- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
- 别名
- CSNK1E (CSNK1E 产品)
- 背景
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Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1E can phosphorylate a large number of proteins. CSNK1E participates in Wnt signaling and is the central component of the circadian clock. It may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. CSNK1E inhibits cytokine-induced granuloytic differentiation.The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: HCKIE, MGC10398, CKIepsilon
Protein Interaction Partner: DVL3, TIAM1, UBC, REST, ZSWIM8, TAZ, SAV1, DVL2, ADAM22, SNX24, AHCYL2, PER1, MCC, HMMR, TCEB2, STK3, SEC13, CSNK1D, CSNK1A1, CRY1, ACACA, FAM83H, FAM83B, VPS13B, FAM199X, KLHDC3, FAM110B, FAM110A, FAM83D, C2orf44, SNX22, STOX2, UNC45A, PPP6R3, WDR5, SDCC
Protein Size: 416 - 分子量
- 47 kDa
- 基因ID
- 1454
- NCBI登录号
- NM_001894, NP_001885
- UniProt
- P49674
- 途径
- Hedgehog Signaling, M Phase
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