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CENPB 抗体 (C-Term)

CENPB 适用: 人, 小鼠, 大鼠, 马, Pig, 绵羊, Cow, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784717
发货至: 中国
  • 抗原 See all CENPB 抗体
    CENPB (Centromere Protein B (CENPB))
    抗原表位
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 马, Pig, 绵羊, Cow, Saccharomyces cerevisiae, 斑马鱼
    宿主
    • 16
    • 2
    克隆类型
    • 18
    多克隆
    标记
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This CENPB antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GGEDSDSDSE EEDDEEEDDE DEDDDDDEED GDEVPVPSFG EAMAYFAMVK
    预测反应
    Cow: 83%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 100%, Sheep: 86%, Yeast: 100%, Zebrafish: 75%
    产品特性
    This is a rabbit polyclonal antibody against CENPB. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CENPB
    Top Product
    Discover our top product CENPB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 599 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CENPB (Centromere Protein B (CENPB))
    别名
    CENPB (CENPB 产品)
    别名
    CENPB antibody, CENP-B antibody, centromere protein B antibody, centromere protein B, 80kDa antibody, CENPB antibody, Cenpb antibody
    背景
    CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, RNF2, NR3C1, FBXO25, CENPA, APP, GFI1B, SUMO2, SMN1, PIN1, GSK3B, GADD45A, CSNK2B, CDKN1A, ANXA7, RPS6KA6, TK1, TAC1, TAF1D, PARP1, PARP2, HAND2, CENPB,
    Protein Size: 599
    分子量
    65 kDa
    基因ID
    1059
    NCBI登录号
    NM_001810, NP_001801
    UniProt
    P07199
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