Adrenomedullin 抗体 (C-Term)
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- 抗原 See all Adrenomedullin (ADM) 抗体
- Adrenomedullin (ADM)
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抗原表位
- C-Term
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适用
- 人, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Adrenomedullin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF
- 预测反应
- Human: 100%, Rabbit: 91%
- 产品特性
- This is a rabbit polyclonal antibody against ADM. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product ADM Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 185 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Adrenomedullin (ADM)
- 别名
- ADM (ADM 产品)
- 别名
- ADM antibody, Ap antibody, H39316 antibody, RATAP antibody, AM antibody, adrenomedullin antibody, ADM antibody, adm antibody, Adm antibody
- 物质类
- Hormone
- 背景
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Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
Alias Symbols: AM
Protein Interaction Partner: CALCRL, EDN1, CFH, MME, ADM,
Protein Size: 185 - 分子量
- 20 kDa
- 基因ID
- 133
- NCBI登录号
- NM_001124, NP_001115
- UniProt
- P35318
- 途径
- Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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