Dynamin 1 抗体 (Middle Region)
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- 抗原 See all Dynamin 1 (DNM1) 抗体
- Dynamin 1 (DNM1)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Dynamin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- PPVDDSWLQV QSVPAGRRSP TSSPTPQRRA PAVPPARPGS RGPAPGPPPA
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against DNM1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DNM1
- Top Product
- Discover our top product DNM1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 851 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Dynamin 1 (DNM1)
- 别名
- DNM1 (DNM1 产品)
- 别名
- DNM antibody, Dnm antibody, AI838169 antibody, Ftfl antibody, mKIAA4093 antibody, dnm antibody, DNM1 antibody, Dnm1 antibody, dnm1 antibody, si:dkey-246l19.2 antibody, dynamin 1 antibody, dynamin-1 antibody, dynamin 1a antibody, DNM1 antibody, Dnm1 antibody, BACOIKO008_37 antibody, PTRG_07818 antibody, PTRG_08097 antibody, dnm1 antibody, LOC100168088 antibody, LOC100199205 antibody, dnm1a antibody
- 背景
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DNM1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: DNM
Protein Interaction Partner: BIN1, SLA1, UBC, GRB2, AMPH, NCL, FANCD2, IRF2BPL, TBC1D2, NPM3, SNRPA1, SNX9, Fcho2, IQCB1, NCK2, NCK1, Asap1, SH3BP4, DNM1, PTK2B, PIAS1, SUMO1, UBE2I, SRC, ITSN1, SH3GL2, DYRK1A, CDK5, ARRB1, Ap2a1, SH3KBP1, DNM2, ADAM2, UBASH3A, KIAA1377, GRIN1, MED31
Protein Size: 851 - 分子量
- 95 kDa
- 基因ID
- 1759
- NCBI登录号
- NM_004408, NP_004399
- UniProt
- P39053
- 途径
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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